Aim: This study aimed to evaluate effectiveness of the coagulation process for reactive blue 19 dye (RB19) removal from textile industry wastewater. Materials and Methods: In this research, coagulation process using three coagulants poly aluminum chloride (PACl), alum, and ferric chloride in the presence of anionic polyelectrolyte and kaolin as coagulants aid were studied for the removal of RB19 dye from synthetic wastewater. The influence of effective parameters such as pH, coagulant dose, initial dye concentration, and addition of coagulants aid was investigated. Results: The results showed that the best dye removal efficiency using three coagulants was archived in neutral pH. Under this condition, the optimum dose of PACl, alum, and ferric chloride was 200, 300, and 400 mg/L and corresponding to dye removal efficiency of 91%, 92%, and 81%, respectively. Addition of polyelectrolyte as a coagulant aid with ferric chloride slightly increased process efficiency, whereas adding polyelectrolyte with alum and PACl slightly decreased dye removal efficiency. By addition of kaolin as a coagulant aid with PACl increased dye removal efficiency about 5%, whereas adding kaolin with alum slightly decreased removal efficiency and can be ignored also, in the case of ferric chloride no significant effect on process efficiency observed in the presence of kaolin. Conclusion: Regarding to obtained results, coagulation can be a robust treatment method for the management of wastewater containing reactive dye.