Aims: The present study aimed to investigate the relationship between traffic noise and drivers' reaction time (RT) and their error in estimates of movement time. Materials and Methods: In over all, 80 university students with at least 3 years postlicense experience of driving were divided into two groups including traffic noise exposure and control group. S5 test of Vienna test system package was used for assessment of RT. In addition, time-movement anticipation was employed for measuring the rate of error in estimation of movement time before exposing to the traffic noise. After a 1-month interval, participants in the experimental group were exposed to traffic noise about 2 h and the tests were performed again for both groups. Results: Accordingly, RT was statistically higher after traffic noise exposure for male and female. However, there was no significant difference between time of movement before and after exposure to traffic noise both for male and female (P > 0.05). In addition, no difference was shown between movement time, number of accurate estimates, and number of estimates with gross errors before and after of traffic noise exposure in experimental and control group. Conclusion: The results suggest that traffic noise may be associated with poorer mental processing, which can result in longer RT during driving. Therefore, traffic noise would expose drivers to consequent accidents and incidents.