Wolters Kluwer - Medknow Wolters Kluwer India Pvt. Ltd. International Journal of Environmental Health Engineering (IJEHE) AWAITED 2022 November 2022 11 29 Designing, manufacturing, and evaluating the performance of active liquid cooling vest in hot laboratory conditions 1 5 26307 10.4103/ijehe.ijehe_9_22 EN Elaheh Dehghani Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-9601-8517 Habibollah Dehghan Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-6526-8601 Journal Article 2022 02 17 <strong>Aim:</strong> The present study aims to design, manufacture, and evaluate the performance of an active liquid cooling vest (ALCV) to control the heat strain in hot laboratory conditions. <strong>Materials and Methods:</strong> An ALCV was designed with a cold liquid circulation system in tubes embedded inside the vest. A performance of ALCV in the hot laboratory conditions with an average temperature of 38.5°C and relative humidity of 40% was done with ALCV and none-ALCV (NALCV). Parameters such as heart rate, oral temperature (OT), thermal sensation (TS), perceived exertion (PE), and chest temperature (CT), forehead temperature (FT), and scapula temperature (ST) were measured. Paired <em>t</em>-test was used to compare the average of the data. <strong>Results:</strong> The results illustrated that the difference between the average temperature of the ST and CT with ALCV and NALCV, it was 2°C ± 0.5°C. There was a statistically significant difference between the average PE and TS in two testing conditions (<em>P</em> < 0.05). Paired <em>t</em>-test showed that there is no significant difference between the average FT and OT in the two testing conditions (<em>P</em> > 0.05). <strong>Conclusion:</strong> Due to the positive effects of the designed ALCV in reducing skin temperature, heat sensation, and PE, this cooling vest can be used as a useful and cost-effective solution to reduce the level of heat strain in hot environments. https://ijehe.mui.ac.ir/article_26307_7899ee4f9d0e8d75201a265cdd6593bf.pdf